compound 3 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TC0036	Compound Lup-20(29)-en-3-yl acetate		IL Receptor , VEGFR , Others , TNF , COX
	Lupeol acetate, a derivative of Lupeol, inhibits the progression of rheumatoid arthritis by downregulating TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B.		IL Receptor , VEGFR , Others , TNF , COX
T11942	MAP4K4-IN-3	Compound 17	MAPK
	MAP4K4-IN-3 (Compound 17) may be a viable target for antidiabetic agents, a serine/threonine protein kinase.		MAPK
TN6410	New compound 3
	New compound 3 can be used for related research in the field of life sciences, and its product number is TN6410.
T11035	DiABZI STING agonist-1 (Tautomerism)	diABZI STING agonist (Compound 3)	STING
	diABZI STING agonist-1 (Tautomerism) (diABZI STING agonist (Compound 3)) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively.		STING
T13017	STL127705	Compound L,7-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-3-(3-fluorophenyl)pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione	DNA-PK , Others
	STL127705 (Compound L) is a potent Ku 70/80 heterodimer protein inhibitor and inhibits Ku70/80-DNA interaction with IC50 of 3.5 μM. STL127705 inhibits the activation of Ku-dependent DNA-PKCS kinase with IC50 of 2.5 μM.		DNA-PK , Others
T10608	BRD5648	(R)-BRD0705	GSK-3
	BRD5648 ((R)-BRD0705) is an inactive (R)-enantiomer of BRD0705. BRD0705 is a GSK3α inhibitor (IC50: 66 nM; Kd: 4.8 μM) and can be used in acute myeloid leukemia (AML) studies.		GSK-3
T9184L	Compound 3344 hydrochloride	4-(2,3-dihydro-1,4-benzodioxin-5-yl)-~{N}-[3-[(dimethylamino)methyl]phenyl]-2-methoxy-aniline hydrochloride(2368246-78-8 free base),Compound 3344 hydrochloride (2368246-78-8 free base)	Ras
	Compound 3344 hydrochloride is an inhibitor of KRAS-effector interactions，with an affnity of 126nm.		Ras
T9658	DCZ3301	NPS ALX Compound 4a hydrochloride(1:1)(299433-10-6 Free base)	Others
	DCZ3301 is a novel aryl-guanidino inhibitor.		Others
T9537	N'-Nitro-D-arginine	N'-Nitro-D-arginine,H-D-Arg(NO2)-OH,(R)-2-Amino-5-(3-nitroguanidino)pentanoic acid	Others
	N'-Nitro-D-arginine (N'-Nitro-D-arginine) is a Building Block.		Others
T7944	VPS34 inhibitor 1 (Compound 19, PIK-III analogue)	PIK-III analogue	PI3K
	VPS34 inhibitor 1 (Compound 19, PIK-III analogue) (PIK-III analogue) is a potent and selective inhibitor of VPS34( IC50 : 15 nM)		PI3K
T6146	Dorsomorphin dihydrochloride	BML-275 2HCl,Compound C dihydrochloride,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride	AMPK , Autophagy , TGF-beta/Smad
	Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity on structurally related kinases.		AMPK , Autophagy , TGF-beta/Smad
T8055	TFEB activator 1	(1E,4E)-1,5-Bis(2-Methoxyphenyl)penta-1,,Curcumin analog compound C1,Curcumin analog C1,RPN77612	Others , Autophagy
	TFEB activator 1 (Curcumin analog compound C1) is an activator of transcription factor EB (TFEB) with promise for the prevention or treatment of Alzheimer's disease.		Others , Autophagy
T64349	Necroptosis-IN-3	Cyclohexanecarboxamide, N-(2-thienylmethyl)-	Necroptosis
	Necroptosis-IN-3 (Cyclohexanecarboxamide, N-(2-thienylmethyl)-) (Compound 69) is a Necroptosis inhibitor that inhibits TNF-α induced necroptosis. Necroptosis-IN-3 (Compound STX1638) also inhibits 11β-HSD1.		Necroptosis
T64350	Casein kinase 1δ-IN-3		Casein Kinase
	Casein kinase 1δ-IN-3 (Casein kinase 1δ-IN-3) (Compound 23a) is a casein kinase 1 delta (CK1d) inhibitor with a pIC50 of 6.5376 M.		Casein Kinase
T5277	3-Furanoic acid	3-Furoic acid,3-Carboxyfuran,3-Furancarboxylic acid	Others , Endogenous Metabolite
	3-Furanoic acid (3-Carboxyfuran) is an organic acid regularly occurring in the urine of healthy individuals. 3-Furanoic acid (3-Carboxyfuran) is also a compound found in honey and honeydew samples.		Others , Endogenous Metabolite
TN1819	Kaempferol 3-neohesperidoside	Kaempferol 3-O-neohesperidoside	GSK-3 , MEK , PI3K
	Kaempferol 3-neohesperidoside (Kaempferol 3-O-neohesperidoside), a flavonoid compound, demonstrates an insulinomimetic effect on the rat soleus muscle.		GSK-3 , MEK , PI3K
TN1264	3'-O-Methylbatatasin III		Antifungal
	3'-O-Methylbatatasin III is a natural compound from the orchid plant Bletilla splendens with antibiotic activity and antispasmodic activity.3'-O-Methylbatatasin III exhibits antifungal activity.3'-O-Methylbatatasin III i...		Antifungal
TN7247	Limocitrin 3-O-sophoroside	Limocitrinyle-3-O-β-D-sophoroside
	Limocitrin 3-O-sophoroside is a compound that can be used in biological research.
T60158	PBRM1-BD2-IN-3		Epigenetic Reader Domain
	PBRM1-BD2-IN-3 (compound 12) is a potent inhibitor of PBRM1-BD2, exhibiting an IC50 value of 1.1 μM, and is utilized in anticancer research.		Epigenetic Reader Domain
T67696	1-(2-fluorophenyl)-3-[5-(2-methoxyphenyl)-1,3,4-thiadiazol-2-yl]urea		Others
	1-(2-fluorophenyl)-3-[5-(2-methoxyphenyl)-1,3,4-thiadiazol-2-yl]urea is a chemical compound.		Others